AKR1C3 is a biomarker and druggable target for oropharyngeal tumors.

Caterina Peraldo-NeiaPaola OstanoMaurizia Mello-GrandFrancesca GuanaIlaria GregnaninDonatella BoschiSimonetta Oliaro-BossoAgnese Chiara PippioneAndrea CarenzoLoris De CeccoStefano CavalieriArianna MicaliFederica PerroneGianluca AveronoPaolo BagnasaccoRiccardo DosdeganiLaura MasiniMarco KrengliPaolo Aluffi-VallettiGuido ValenteGiovanna Chiorino

Published in: Cellular oncology (Dordrecht) (2020)

We identified AKR1C3 as a potential prognostic biomarker in OPSCC and as a potential drug target whose inhibition can potentiate the effect of Cisplatin.

Keyphrases

human health
emergency department
drug induced
electronic health record