A sprinkle of salt in the pressure cooker of innate immunity and inflammation.
Matthew J SweetSarah A JonesJames HarrisPublished in: Immunology and cell biology (2020)
In this issue, Schroder et al. assess the impacts of mechanical strain and salt on macrophage inflammatory responses in vitro. They demonstrate a complex role for the transcription NFAT5 in cytokine release in response to stress, strain and salt in the context of orthodontic treatments.