Aggregation-induced emission based one-step "lighting up" sensor array for rapid protein identification.

Xuan ZhaoYuhuan GaoJun WangYating ZhanXin LuShenghao Xu Xi-Liang Luo

Published in: Chemical communications (Cambridge, England) (2021)

Based on the distinct fingerprint-like fluorescence responses generated by different electrostatic and hydrophobic interactions between three kinds of self-designed water-soluble aggregation-induced emission (AIE) fluorogens (AIEgens) and proteins, a fast responsive (10 min) and one-step "lighting up" fluorescent sensor array for rapid protein discrimination was developed.

Keyphrases

water soluble
high resolution
living cells
protein protein
loop mediated isothermal amplification
amino acid
binding protein
single molecule
high density
fluorescent probe
cancer therapy
ionic liquid
small molecule
single cell
quality control
energy transfer