Changes in signalling from faecal neuroactive metabolites following dietary modulation of IBS pain.
Caroline J TuckAmal Abu OmarGiada De PalmaSamira OsmanNestor N Jimenez-VargasYang YuSean Mp BennetCintya Lopez-LopezJosue O Jaramillo-PolancoCorey C BakerAidan Sw BennettMabel Guzman-RodriguezQuentin TsangTaylor AlwardSebastien RollandCeline MorissetteElena F VerduPremysl BercikStephen J VannerAlan E LomaxDavid E ReedPublished in: Gut (2022)
In a subset of IBS patients with improvement in abdominal pain following a LFD, there is a decrease in pronociceptive signalling from FS, suggesting that changes in luminal mediators may contribute to symptom response.