CD19 CAR T-Cell Therapy in Autoimmune Disease - A Case Series with Follow-up.
Fabian MüllerJule TaubmannLaura BucciArtur WilhelmChristina BergmannSimon VölklMichael AignerTobias RotheIoanna MinopoulouCarlo TurJohannes KnitzaSoraya KharboutliSascha KretschmannIngrid VasovaSilvia SpoerlHannah ReimannLuis MunozRoman G GerlachSimon SchäferRicardo Grieshaber-BouyerAnne-Sophie KorganowDominique Farge-BancelDimitrios MougiakakosAline BozecThomas WinklerGerhard KrönkeAndreas MackensenGeorg SchettPublished in: The New England journal of medicine (2024)
In this case series, CD19 CAR T-cell transfer appeared to be feasible, safe, and efficacious in three different autoimmune diseases, providing rationale for further controlled clinical trials. (Funded by Deutsche Forschungsgemeinschaft and others.).