Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition.
Eugenia RoupakiaEvangelia ChavdoulaGeorgia KarpathiouGiannis VatsellasDimitrios ChatzopoulosAngeliki MelaJennifer M GilletteKatharina KriegsmannMark KriegsmannAnna BatistatouAnna GoussiaKenneth B MarcuEmmanouil KarterisApostolos KlinakisEvangelos KolettasPublished in: Cancers (2021)
Canonical NF-κB signalling promotes NSCLC, in part, by downregulating the metastasis suppressor CD82/KAI1 which inhibits cell migration, EMT and tumour growth.