Segmentation of Static and Dynamic Atomic-Resolution Microscopy Data Sets with Unsupervised Machine Learning Using Local Symmetry Descriptors.
Ning WangChristoph FreysoldtSiyuan ZhangChristian H LiebscherJörg NeugebauerPublished in: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada (2021)
We present an unsupervised machine learning approach for segmentation of static and dynamic atomic-resolution microscopy data sets in the form of images and video sequences. In our approach, we first extract local features via symmetry operations. Subsequent dimension reduction and clustering analysis are performed in feature space to assign pattern labels to each pixel. Furthermore, we propose the stride and upsampling scheme as well as separability analysis to speed up the segmentation process of image sequences. We apply our approach to static atomic-resolution scanning transmission electron microscopy images and video sequences. Our code is released as a python module that can be used as a standalone program or as a plugin to other microscopy packages.
Keyphrases
- deep learning
- machine learning
- electron microscopy
- single molecule
- convolutional neural network
- big data
- artificial intelligence
- high resolution
- optical coherence tomography
- high speed
- electronic health record
- high throughput
- label free
- single cell
- quality improvement
- mass spectrometry
- data analysis
- anti inflammatory