Prescription of memantine during non-stereotactic, brain-directed radiation among patients with brain metastases: a population-based study.

Nayan LambaElie MehannaRachel B KearneyPaul J CatalanoPaul D BrownDaphne A Haas-KoganAyal A Aizer

Published in: Journal of neuro-oncology (2020)

Despite phase 3 evidence supporting memantine utilization among patients receiving WBRT, our population-based study indicates that rates of memantine prescription are strikingly low, although memantine utilization seems to be increasing since publication of RTOG 0614. Further investigation is needed to identify provider and practice-related barriers preventing incorporation of memantine into management paradigms.

Keyphrases

brain metastases
small cell lung cancer
primary care
white matter
resting state
radiation therapy
multiple sclerosis
radiation induced
functional connectivity