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Metabolic syndrome and the plasma proteome: from association to causation.

Mohamed A ElhadadRory WilsonShaza B ZaghloolCornelia HuthChristian GiegerHarald GrallertJohannes GraumannWolfgang RathmannWolfgang KoenigMoritz F SinnerKristian HveemKarsten SuhreBarbara ThorandChristian JonassonMelanie WaldenbergerAnnette Peters
Published in: Cardiovascular diabetology (2021)
Our findings offer new insights into the plasma proteome underlying MetS and identify new protein associations. We reveal possible casual effects of APOE2, APOB and RET on MetS. Our results highlight protein candidates that could potentially serve as targets for prevention and therapy.
Keyphrases
  • metabolic syndrome
  • protein protein
  • amino acid
  • high fat diet
  • type diabetes
  • stem cells
  • single cell
  • adipose tissue
  • dna methylation
  • small molecule
  • cell therapy