Metabolic syndrome and the plasma proteome: from association to causation.

Mohamed A ElhadadRory WilsonShaza B ZaghloolCornelia HuthChristian GiegerHarald GrallertJohannes GraumannWolfgang RathmannWolfgang KoenigMoritz F SinnerKristian HveemKarsten SuhreBarbara ThorandChristian JonassonMelanie WaldenbergerAnnette Peters

Published in: Cardiovascular diabetology (2021)

Our findings offer new insights into the plasma proteome underlying MetS and identify new protein associations. We reveal possible casual effects of APOE2, APOB and RET on MetS. Our results highlight protein candidates that could potentially serve as targets for prevention and therapy.

Keyphrases

metabolic syndrome
protein protein
amino acid
high fat diet
type diabetes
stem cells
single cell
adipose tissue
dna methylation
small molecule
cell therapy