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Aiming off the target: recycling target capture sequencing reads for investigating repetitive DNA.

Lucas CostaAndré MarquesChris BuddenhagenWilliam Wayt ThomasBruno HuettelVeit SchubertSteven DodsworthAndreas HoubenGustavo SouzaAndrea Pedrosa-Harand
Published in: Annals of botany (2021)
Our results show that off-target TCS reads can be recycled to identify repeats for cyto- and phylogenomic investigations. Given the growing availability of TCS reads, driven by global phylogenomic projects, our strategy represents a way to recycle genomic data and contribute to a better characterization of plant biodiversity.
Keyphrases
  • high frequency
  • single cell
  • electronic health record
  • single molecule
  • copy number
  • gene expression
  • big data
  • artificial intelligence