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Transcription factors and splice factors - interconnected regulators of stem cell differentiation.

Madison M MehlferberMuge Kuyumcu-MartinezClint L MillerGloria M Sheynkman
Published in: Current stem cell reports (2023)
Overall, gene and splice regulatory networks are important in defining cell state. The emerging high-throughput systems-level approaches will characterize the gene regulatory network components necessary in driving stem cell differentiation.
Keyphrases
  • transcription factor
  • high throughput
  • single cell
  • genome wide identification
  • dna binding
  • cell therapy
  • genome wide
  • copy number
  • stem cells
  • gene expression
  • dna methylation
  • mesenchymal stem cells
  • genome wide analysis