Orally Ingested Probiotics, Prebiotics, and Synbiotics as Countermeasures for Respiratory Tract Infections in Non-elderly Adults: A Systematic Review and Meta-analysis.

Julie L ColemanAdrienne Hatch-McChesneyStephanie D SmallJillian T AllenElaine SulloRichard T AgansHeather S FagnantAsma S BukhariJ Philip Karl

Published in: Advances in nutrition (Bethesda, Md.) (2022)

Orally ingested probiotics, relative to placebo, modestly reduce the incidence, duration and severity of RTI in non-elderly adults. Physical activity and delivery matrix may moderate some of these effects. Whether prebiotic and synbiotic interventions confer similar protection remains unclear due to few relevant studies. PROSPERO registration: CRD42020220213.

Keyphrases

respiratory tract
physical activity
middle aged
community dwelling
risk factors
clinical trial
double blind
sleep quality
case control