Effect of GLP-1/GLP-1R on the Polarization of Macrophages in the Occurrence and Development of Atherosclerosis.
Li YangLong ChenDongfeng LiHao XuJishun ChenXinwen MinMeian HeTangchun WuJi-Xin ZhongHandong YangJun ChenPublished in: Mediators of inflammation (2021)
GLP-1R agonist is independent of the hypoglycemic effect of T2DM and has protective effect on cardiovascular system. GLP-1R may regulate the polarization of macrophages toward M2, thus playing a protective role in the progression of coronary atherosclerosis.