Metal-Free Intramolecular Aminophosphination of Allenes.

Zhantao YangZhenzhen SunNingning ZhuWenyan LiMeng HanYan Qiao Chun-Hua Yang Jun-Biao Chang

Published in: The Journal of organic chemistry (2020)

A metal-free intramolecular aminophosphination of sulfonamidoallenes with diarylphosphine oxides and Tf2O was developed. This method offers a general and practical procedure to construct valuable alkenylphosphine-substituted N-heterocycles via the bifunctionalization reaction of allenes in good yields under mild conditions.

Keyphrases

energy transfer
molecular docking
minimally invasive