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Immunotherapy in Older Patients with Cancer: A Narrative Review.

Alexandra SmithJeffrey Mathew BobySteve Joseph BennyNadia GhazaliElke VermeulenMathew George
Published in: International journal of general medicine (2024)
Enhanced clinical benefits along with better tolerability associated with immunotherapies make it an attractive alternative to conventional chemotherapeutic drugs, especially in elderly patients. There is currently a limited number of studies assessing the clinical outcomes of immunotherapies, particularly in the elderly. Overall, our findings reflect a need for further prospective studies focussing on geriatric patients representative of the real-life population, in order to derive a more precise understanding of the clinical utility, toxicity profile, and cost-effectiveness of immune checkpoint inhibitors in older patients with cancer.
Keyphrases
  • community dwelling
  • middle aged
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • physical activity
  • case control
  • prognostic factors
  • open label
  • oxidative stress
  • cross sectional
  • clinical trial
  • study protocol