The Impact of Prior Single-Gene Testing on Comprehensive Genomic Profiling Results for Patients with Non-Small Cell Lung Cancer.

Mary K NeslineVivek SubbiahRebecca A PrevisKyle C StricklandHeidi KoPaul DePietroMichael D BiornMaureen CooperNini WuJeffrey ConroySarabjot PablaShengle ZhangZachary D WallenPratheesh SathyanKamal SainiMarcia EisenbergBrian CaveneyEric A SeversonShakti Ramkissoon

Published in: Oncology and therapy (2024)

For patients with NSCLC, initial use of SGT increases subsequent CGP test cancellations, turnaround time, and the likelihood of incomplete molecular profiling for guideline-recommended biomarkers due to tissue insufficiency.

Keyphrases

copy number
single cell
small cell lung cancer
genome wide
advanced non small cell lung cancer
gene expression