Gut microbiome in ADHD and its relation to neural reward anticipation.
Esther AartsThomas H A EderveenJilly NaaijenMarcel P ZwiersJos BoekhorstHarro M TimmermanSanne P SmeekensMihai G NeteaJan K BuitelaarBarbara FrankeSacha A F T van HijumAlejandro Arias VasquezPublished in: PloS one (2017)
Our results show increases in gut microbiome predicted function of dopamine precursor synthesis between ADHD cases and controls. This increase in microbiome function relates to decreased neural responses to reward anticipation. Decreased neural reward anticipation constitutes one of the hallmarks of ADHD.