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Neurofilaments as Biomarkers for Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis.

Zhouwei XuRobert David HendersonMichael DavidPamela Ann McCombe
Published in: PloS one (2016)
NF heavy and light chain levels have potential use as a marker of neural degeneration in ALS, but are not specific for the disease, and are more likely to be used as measures of disease progression.
Keyphrases
  • amyotrophic lateral sclerosis
  • signaling pathway
  • lps induced
  • oxidative stress
  • pi k akt
  • nuclear factor
  • human health
  • risk assessment
  • climate change
  • toll like receptor