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Mitochondrial DNA Copy-Number Variation and Pancreatic Cancer Risk in the Prospective EPIC Cohort.

Manuel GentiluomoVerena A KatzkeRudolf KaaksAnne TjønnelandGianluca SeveriVittorio PerducaMarie-Christine Boutron-RuaultElisabete WeiderpassPietro FerrariTheron JohnsonMatthias B SchulzeManuela M BergmannAntonia TrichopoulouAnna KarakatsaniCarlo La VecchiaDomenico PalliSara GrioniSalvatore PanicoRosario TuminoCarlotta SacerdoteBas Bueno-de-MesquitaRoel VermeulenTorkjel M SandangerJ Ramón QuirósMiguel Rodriguez-BarrancoPilar AmianoSandra Colorado-YoharEva ArdanazMalin SundKay-Tee KhawNicholas J WarehamJulie A SchmidtPaula JakszynLuca MorelliFrederico CanzianDaniele Campa
Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2020)
Our findings highlight the importance of understanding the mitochondrial biology in pancreatic cancer.
Keyphrases
  • mitochondrial dna
  • copy number
  • genome wide
  • oxidative stress
  • dna methylation
  • gene expression