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Prevention of adhesions post-abdominal surgery: Assessing the safety and efficacy of Chitogel with Deferiprone in a rat model.

Rajan Sundaresan VediappanCatherine BennettClare CooksleyJohn FinnieMarkus TrochslerRyan David QuarringtonClaire F JonesAhmed BassiouniStephen MorattiAlkis J PsaltisGuy MaddernSarah VreugdeP J Wormald
Published in: PloS one (2021)
Chitogel with Deferiprone 1 mM constitutes an effective preventative anti-adhesion barrier after abdominal surgery in a rat model. Moreover, this therapeutic combination of agents is safe and does not weaken the healing of the sutured enterotomy site.
Keyphrases
  • biofilm formation
  • pseudomonas aeruginosa
  • staphylococcus aureus
  • cell adhesion