Efficacy of teplizumab for treatment of type 1 diabetes: A meta-analysis of randomized controlled trials.

Ehsan HeidariArman ShafieeShahab NoorianMohammad Ali RafieiMohammad AbbasiMohammad Javad AminiOmid SafariFatemeh AghamahdiMahmood Bakhtiyari

Published in: Diabetes/metabolism research and reviews (2024)

Teplizumab has a significant impact on reducing insulin dependence and enhancing endogenous insulin production in T1DM patients. However, its effect on long-term glycaemic control, as indicated by HbA1c levels, remains inconclusive.

Keyphrases

type diabetes
glycemic control
end stage renal disease
ejection fraction
newly diagnosed
systematic review
adipose tissue
metabolic syndrome