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I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations.

Daniel Clark FilesMichael A MatthayCarolyn S CalfeeNeil R AggarwalAdam L AsareJeremy R BeitlerPaul A BergerEllen L BurnhamGeorge CiminoMelissa H ColemanAlessio CrippaAndrea DiscacciatiSheetal GandotraKevin W GibbsPaul T HendersonCaroline A G IttnerAlejandra JaureguiKashif T KhanJonathan L KoffJulie LangMary LaRoseJoe LevittRuixiao LuJeffrey D McKeehanNuala J MeyerDerek W RussellKarl W ThomasMartin EklundLaura J EssermanKathleen D Liunull nullnull null
Published in: BMJ open (2022)
NCT04488081.
Keyphrases
  • respiratory failure
  • coronavirus disease
  • sars cov
  • extracorporeal membrane oxygenation
  • mechanical ventilation
  • clinical trial
  • study protocol
  • liver failure
  • intensive care unit
  • single cell