Accumulation of CD103+ CD8+ T cells in a cutaneous melanoma micrometastasis.

Katharina HochheiserHan Xian Aw YeangTeagan WagnerCandani TutukaAndreas BehrenJason WaithmanChristopher AngelPaul J NeesonThomas GebhardtDavid E Gyorki

Published in: Clinical & translational immunology (2019)

Such results support the emerging concept that CD103+ CD8+ TRM cells are key mediators of cancer surveillance and imply an important function of these cells in controlling clinically occult micrometastases in humans.

Keyphrases

induced apoptosis
cell cycle arrest
public health
endoplasmic reticulum stress
signaling pathway
cell death
squamous cell carcinoma
squamous cell
childhood cancer