Significant Inter- and Intralaboratory Variation in Gleason Grading of Prostate Cancer: A Nationwide Study of 35,258 Patients in The Netherlands.
Rachel N FlachPeter-Paul M WillemseBritt B M SuelmannIvette A G DeckersTrudy N JongesCarmen van DooijeweertPaul J van DiestRichard P MeijerPublished in: Cancers (2021)
Substantial variation in prostate cancer grading was observed between and within Dutch pathology laboratories. Case-mix correction did not explain the variation. Better standardization of prostate cancer grading is warranted to optimize and harmonize treatment.