Association of gestational free and total triiodothyronine with gestational hypertension, preeclampsia, preterm birth and birth weight: an individual-participant data meta-analysis.
Arash DerakhshanTuija MännistöLiangmiao ChenJoris A J OsingaGhalia AshoorXuemian LuSofie BliddalFang-Biao TaoSuzanne J BrownBijay VaidyaAndrew T HattersleySachiko ItohPolina V PopovaAshraf AminorroayaReiko KishiMaryam KianpourElena A VasukovaAbel López-BermejoEmily OkenLeda ChatziMarina VafeiadiWichor M BramerJudit BassolsAitana LertxundiAna Fernández-SomoanoPaula CarrascoJuha AuvinenKun HuangUlla Feldt-RasmussenElena N GrinevaErik K AlexanderElizabeth N PearceLayal ChakerJohn P WalshRobin P PeetersMònica GuxensEila SuvantoKypros H NicolaidesTim I M KorevaarPublished in: The Journal of clinical endocrinology and metabolism (2023)
This study provides new insights on the association of gestational FT3 and TT3 with major adverse pregnancy outcomes which form the basis for future studies required to elucidate the effects of thyroid function on pregnancy outcomes. Based on the current study, routine FT3 or TT3 measurements for the assessment of thyroid function during pregnancy do not seem to be of added value in the risk assessment for adverse outcomes.
Keyphrases
- pregnancy outcomes
- pregnant women
- birth weight
- weight gain
- preterm birth
- gestational age
- risk assessment
- systematic review
- blood pressure
- body mass index
- case control
- emergency department
- machine learning
- heavy metals
- electronic health record
- meta analyses
- weight loss
- big data
- current status
- artificial intelligence
- adverse drug