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Analysis of Amount, Size, Protein Phenotype and Molecular Content of Circulating Extracellular Vesicles Identifies New Biomarkers in Multiple Myeloma.

Ilaria LaurenzanaStefania TrinoDaniela LamorteMarco GirasoleSimone DinarelliAngelo De StradisVitina GriecoMaddalena MaiettiAntonio TraficanteTeodora StatutoOreste VillaniPellegrino MustoAlessandro SgambatoLuciana De LucaAntonella Caivano
Published in: International journal of nanomedicine (2021)
Overall, our cEV based procedure can play an important role in malignancy biomarker discovery and then in real-time tumor monitoring using minimal invasive samples. From a practical point of view, it is smart (small sample volume), rapid (two hours), easy (no specific expertise required) and requirements are widely available in clinical laboratories.
Keyphrases
  • multiple myeloma
  • small molecule
  • genome wide
  • protein protein
  • minimally invasive
  • high throughput
  • gene expression
  • single molecule
  • binding protein
  • loop mediated isothermal amplification