Chronic obstructive pulmonary disease may complicate Alzheimer's disease: a comorbidity problem.
Giacomo TondoFabiola De MarchiEmanuela TerazziPaolo PrandiMarta SacchettiCristoforo ComiRoberto CantelloPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2018)
COPD is known to be associated with the development of cognitive deficits, in particular, regarding for executive functions and attention, memory and logical reasoning. In this context, MMSE has a low diagnostic accuracy to underline effective cognitive impairment in AD-COPD. Our study shows a higher frequency of frontal deficits and behavioral disturbances in patients with AD and COPD than patients with AD-only. COPD could complicate the management of AD patients, thus necessitating a closer and multidisciplinary monitoring.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- working memory
- cognitive impairment
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- traumatic brain injury
- cystic fibrosis
- peritoneal dialysis
- cognitive decline
- functional connectivity
- patient reported outcomes
- quality improvement