Characterisation and outcomes of ARDS secondary to pneumonia in patients with and without SARS-CoV-2: a single-centre experience.
Rahul Y MahidaMinesh ChotaliaJoseph AldermanChhaya PatelAmber HaydenRuchi DesaiEmily BeesleyLouise E CrowleyMarina SoltanMansoor BangashDhruv ParekhJaimin PatelDavid R ThickettPublished in: BMJ open respiratory research (2020)
The clinical syndromes and respiratory mechanics of SARS-CoV-2 and CAP-ARDS are broadly similar. However, SARS-CoV-2 patients initially have a lower requirement for vasopressor support, fewer circulating leukocytes and require prolonged ventilation support. Further studies are required to determine whether the dysregulated inflammation observed in SARS-CoV-2 ARDS may contribute to the increased duration of respiratory failure.
Keyphrases
- sars cov
- respiratory failure
- mechanical ventilation
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- respiratory syndrome coronavirus
- end stage renal disease
- intensive care unit
- newly diagnosed
- oxidative stress
- chronic kidney disease
- ejection fraction
- prognostic factors
- peritoneal dialysis
- coronavirus disease
- metabolic syndrome
- skeletal muscle
- insulin resistance