Determination of Inhibitory Effect of PKM2 Enzyme and Antitumoral Activity of Novel Coumarin-Naphthoquinone Hybrids.
Amanda de A BorgesGabriel OuverneyAfonso T S ArrudaAmanda V RibeiroRuan C B RibeiroAcácio S SouzaAnna Carolina C da FonsecaLucas N Nicolau de QueirozElan C P de AlmeidaBruno PontesVitor W RabeloVitor F FerreiraPaula A AbreuFernando de Carvalho da SilvaLuana da S M ForeziBruno K RobbsPublished in: Current medicinal chemistry (2024)
We assert that compound 6e shows promise as a potential lead for a novel chemotherapeutic drug targeting OSCC, with potential applicability to other cancer types.