Prevalence of Germline Pathogenic and Likely Pathogenic Variants in Patients With Second Breast Cancers.

Katharine A Yao KJacob W Clifford Shuwei Li Holly LaDuca Peter J HulickStephanie GutierrezMary Helen Black

Published in: JNCI cancer spectrum (2020)

Women with P/LP variants in breast cancer predisposition genes are more likely to have SBC than noncarriers. Prospective studies are needed confirm these findings.

Keyphrases

copy number
genome wide
risk factors
dna repair
case control
dna methylation
gene expression
oxidative stress
young adults
transcription factor
childhood cancer