Changes in Endocan and Dermatan Sulfate Are Associated with Biomechanical Properties of Abdominal Aortic Wall during Aneurysm Expansion and Rupture.
Susanne MetschlLukas BruderValentina PaloschiKatharina JakobBenedikt ReutersbergChristian ReepsLars MaegdefesselMichael GeeHans-Henning EcksteinJaroslav PelisekPublished in: Thrombosis and haemostasis (2022)
Our findings reveal a structural association between collagen and PGs and their response to changes in mechanical loads in AAA. Particularly Col1 and endocan reflect the mechano-biological conditions of the aortic wall also in the patient's serum and might serve for AAA risk stratification.