Validation of a Saliva-Based Test for the Molecular Diagnosis of SARS-CoV-2 Infection.
Michela BulfoniEmanuela SozioBarbara MarconMaria De MartinoDaniela CesselliChiara De CarloRomina MartinellaAngelica MigottiEleonora VaniaAgnese Zanus-FortesJessica De PieroEmanuele NencioniCarlo TasciniMiriam IsolaFrancesco CurcioPublished in: Disease markers (2022)
RT-PCR assays conducted on a stored saliva sample achieved similar performance to those on NP swabs, and this may provide a very effective tool for population screening and diagnosis. Collection of saliva in a stabilizing solution makes the test more convenient and widely available; furthermore, the denaturing properties of the solution reduce the infective risks belonging to sample manipulation.