Recognition of Philadelphia chromosome-like acute lymphoblastic leukemia as part of routine diagnostic work-up.
Helena PodgornikAna Doplihar KebeJurka KlunKatarina ReberšekSandra ŠućurovićMatevž ŠkergetSamo ZverPublished in: International journal of laboratory hematology (2021)
The obtained frequencies, and genetic and patients' characteristics are in concordance with the literature data, ensuring a reliable detection of this challenging ALL subtype. The proposed algorithm allows detection of Ph-like ALL at reasonable cost and acceptable workload.
Keyphrases
- acute lymphoblastic leukemia
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- systematic review
- loop mediated isothermal amplification
- machine learning
- copy number
- real time pcr
- label free
- peritoneal dialysis
- electronic health record
- prognostic factors
- big data
- gene expression
- clinical practice
- deep learning
- patient reported outcomes
- patient reported
- neural network