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Multiple sebaceous tumors in a 58-year-old man with colorectal cancer.

Ben Rejeb MohamedSana MokniMaha Ben RejebNihed AbdelmoulaBaderedine SrihaHabib KhochteliMohamed Denguezli
Published in: Clinical case reports (2022)
The Muir-Torre Syndrome is a rare genodermatosis, defined by the occurrence of sebaceous neoplasia and internal malignancies and caused by mutations in the mismatch repair gene. We describe the case of 58-year-old man who, over the course of several years, had multiple skin lesions and colon cancer. The syndrome was diagnosed using Sanger sequencing, which allowed us to find the causative mutation.
Keyphrases
  • case report
  • risk assessment
  • high grade
  • single cell
  • genome wide
  • copy number
  • gene expression