Nonlesional diffusely abnormal appearing white matter in clinically isolated syndrome: Prevalence, association with clinical and MRI features, and risk for conversion to multiple sclerosis.
R Davis HolmesIrene M VavasourJamie GreenfieldGuojun ZhaoJimmy S LeeG R Wayne MooreRoger TamLuanne M MetzAnthony TrablouseeDavid K B LiCornelia LaulePublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2021)
DAWM is present in a similar proportion of patients with CIS and clinically definite MS, and it is associated with increased risk of conversion to MS over 6 months.