Efficacy and safety of direct oral anticoagulants in patients with atrial fibrillation combined with chronic kidney disease: a systematic review and meta-analysis.

Yaodi LiShuyi WuJintuo ZhouJin-Hua Zhang

Published in: Thrombosis journal (2024)

Compared with VKAs, DOACs may increase efficacy and improve safety in AF patients with CKD (90 ml/min> Crcl≥15 ml/min), and shows at least similar efficacy and safety in AF patients with Kidney failure (Crcl<15 ml/min).

Keyphrases

direct oral anticoagulants
atrial fibrillation
chronic kidney disease
venous thromboembolism
end stage renal disease
peritoneal dialysis