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Atherogenic dyslipidemia, but not hyperglycemia, is an independent factor associated with liver fibrosis in subjects with type 2 diabetes and NAFLD: a population-based study.

María Teresa JuliánGuillem PeraBerta SoldevilaLlorenç CaballeríaJosep JulveCarlos Puig-JovéRosa MorillasPere ToránCarmen ExpósitoManel Puig-DomingoEsmeralda CastelblancoJosep Franch-NadalKenneth CusiDidac MauricioNuria Alonso
Published in: European journal of endocrinology (2021)
Factors associated with moderate-to-advanced liver fibrosis in NAFLD are different in subjects with and without T2D. Atherogenic dyslipidemia was associated with the presence of moderate-to-advanced liver fibrosis in T2D with NAFLD but not in non-diabetic subjects. These findings highlight the need for an active search for liver fibrosis in subjects with T2D NAFLD and atherogenic dyslipidemia.
Keyphrases
  • liver fibrosis
  • high intensity
  • type diabetes
  • low density lipoprotein
  • oxidative stress
  • wound healing