Postmenopausal women with irritable bowel syndrome (IBS) have more severe symptoms than premenopausal women with IBS.
Adrienne LenhartBruce D NaliboffWendy ShihArpana GuptaKirsten TillischCathy LiuEmeran A MayerLin ChangPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
Postmenopausal women with IBS have more severe IBS symptoms than premenopausal women, while no comparable age-related changes were seen in IBS men. The modulatory effect of female sex hormones on brain-gut interactions which affect visceral perception and GI function likely contributes to these findings.
Keyphrases
- irritable bowel syndrome
- postmenopausal women
- bone mineral density
- breast cancer risk
- early onset
- polycystic ovary syndrome
- insulin resistance
- type diabetes
- sleep quality
- white matter
- multiple sclerosis
- physical activity
- body composition
- depressive symptoms
- pregnancy outcomes
- metabolic syndrome
- middle aged
- skeletal muscle
- brain injury