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Experimental confirmation and bioinformatics reveal biomarkers of immune system infiltration and hypertrophy ligamentum flavum.
Fei Liu
Min Zhong
Lei Yang
Chao Song
Chaoqi Chen
Zhiwei Xu
Chi Zhang
Zhifa Li
Xiaofei Wu
Chen Jiang
Feng Chen
Qian Yan
Published in:
JOR spine (2024)
The TGF-β signaling pathway, TNF signaling pathway, and related hub genes play crucial roles in the progression of ligamentum flavum hypertrophic. Our study may guide future research on fibrosis of the ligamentum flavum.
Keyphrases
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signaling pathway
pi k akt
genome wide
epithelial mesenchymal transition
induced apoptosis
transforming growth factor
bioinformatics analysis
rheumatoid arthritis
current status
single cell
cell proliferation
endoplasmic reticulum stress