Starting stiripentol in adults with Dravet syndrome? Watch for ammonia and carnitine.

Quratulain Zulfiqar Ali Paula Teixeira Marques Arunan SelvarajahSepideh TabarestaniTara SadowayDanielle M Andrade

Published in: Epilepsia (2020)

We report hyperammonemia in adult STP-naive patients who were on valproate and clobazam, despite dose reduction of the latter drugs. We also report that treatment with carnitine improved hyperammonemia, allowing the continuation of STP.

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