Data-driven optimization of version 9 American Joint Committee on Cancer staging system for anal cancer.
Lauren M JanczewskiAmanda BrownerJoseph CotlerHeidi NelsonKarla V BallmanMichael LeBlancMarc J GollubCathy EngJames D BrierleyJoel M PalefskyRichard M GoldbergKaryn A GoodmanM Kay WashingtonElliot A AsareBryan PalisPublished in: Cancer (2023)
The 8th edition AJCC survival data demonstrated a lack of hierarchical prognostic order and informed revised stage groupings in the version 9 AJCC staging system for anal cancer. Thus, a validated data-driven optimization approach can be implemented for staging revisions across all disease sites moving forward.