Genetic Susceptibility to Mood Disorders and Risk of Stroke: A Polygenic Risk Score and Mendelian Randomization Study.

Jiangming Sun Yan Borné Andreas EdsfeldtYunpeng WangMengyu PanOlle MelanderGunnar Engström Isabel Goncalvesnull null

Published in: Stroke (2023)

Our results suggest a causal role of mood disorders in the risk of stroke. High-risk women could be identified early in life using polygenic risk scores to ultimately prevent mood disorders and strokes.

Keyphrases

bipolar disorder
atrial fibrillation
sleep quality
polycystic ovary syndrome
type diabetes
genome wide
pregnant women
adipose tissue
skeletal muscle
subarachnoid hemorrhage