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CC16 levels correlate with cigarette smoke exposure in bronchial epithelial cells and with lung function decline in smokers.

David Chi Leung LamHoi-Hin KwokWai-Cho YuFanny Wai-San KoCheuk-Yin TamArthur Chun-Wing LauDaniel Yee-Tak FongMary Sau-Man Ip
Published in: BMC pulmonary medicine (2018)
Results of these clinical and laboratory investigations suggested that low serum CC16 was associated with smoking-related decline in lung function, demonstrated the first time in a Chinese cohort. The data also lend support to the putative role of CC16 in protection against smoking-related bronchial epithelial damage. (Abstract word count: 243) US CLINICAL TRIAL REGISTRY: NCT01185652 , first posted 20 August, 2010.
Keyphrases
  • lung function
  • cystic fibrosis
  • chronic obstructive pulmonary disease
  • air pollution
  • smoking cessation
  • clinical trial
  • study protocol
  • machine learning
  • big data
  • electronic health record
  • data analysis