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Deletions of pfhrp2 and pfhrp3 genes of Plasmodium falciparum from Honduras, Guatemala and Nicaragua.

Gustavo Adolfo Fontecha SandovalRosa E MejíaEngels BanegasMaria Paz AdeLisandro MendozaBryan OrtizIsaac SabillónGerardo AlvaradoGabriela MatamorosAlejandra Pinto
Published in: Malaria journal (2018)
This study provides molecular evidence of the existence of P. falciparum isolates lacking the pfhrp2 and pfhrp3 genes, and their flanking regions, in Honduras, Guatemala and Nicaragua. This finding could hinder progress in the control and elimination of malaria in Central America. Continuous evaluation of RDTs and molecular surveillance would be recommended.
Keyphrases
  • plasmodium falciparum
  • genome wide
  • public health
  • bioinformatics analysis
  • genome wide identification