In atrial fibrillation epilepsy risk differs between oral anticoagulants: active comparator, nested case-control study.
Katharina PlatzbeckerHelge Müller-FielitzRonja ForaitaMatthias J KoeppAnnemarie VossRené PflockRoland LinderIris PigeotCristina RebordosaMarkus SchwaningerPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2023)
In patients with AF initiating oral anticoagulation, treatment with a DOAC was associated with an increased risk of epilepsy compared to the vitamin K antagonist PPC. Covert brain infarction may explain the observed elevated risk of epilepsy.
Keyphrases
- atrial fibrillation
- oral anticoagulants
- direct oral anticoagulants
- catheter ablation
- left atrial appendage
- left atrial
- heart failure
- percutaneous coronary intervention
- venous thromboembolism
- resting state
- temporal lobe epilepsy
- white matter
- multiple sclerosis
- blood brain barrier
- left ventricular
- brain injury
- smoking cessation