The predictive value of bone turnover markers during discontinuation of alendronate: the PROSA study.

Anne Sophie Koldkjær Sølling Torben HarsløfN H BruunBente Lomholt Langdahl

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2021)

In patients discontinuing ALN, BMD decreased significantly and BTMs increased within the reference range over 2 years. An increase in p-CTX after 3 months was associated with greater bone loss at the hip confirming that maintenance of BMD during treatment discontinuation is dependent on continued suppression of bone turnover.

Keyphrases

bone loss
bone mineral density
end stage renal disease
postmenopausal women
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
body composition
peritoneal dialysis
escherichia coli
klebsiella pneumoniae
multidrug resistant
total hip arthroplasty