Changes of serum growth factors profiles in patients with venous thromboembolism.

Mohammad Abdulhameed Al-QudahHaitham QandeelNabil Al-ZoubiAhmad AlqudahMohammad Bani-AhmadAbdallah Alzoubi

Published in: Scandinavian journal of clinical and laboratory investigation (2017)

Serum profiles of Ang-1, Ang-2 and EGF change dramatically during VTE. This hints the significant role that these growth factors played in the pathogenesis of VTE. Thus, serum levels of growth factors may help in the first-time diagnosis of VTE, but not in diagnosing a recurrent episode of VTE. Larger studies are required to determine 'threshold levels' or 'likelihood ranges' of each biomarker for accurate diagnosis.

Keyphrases

venous thromboembolism
direct oral anticoagulants
angiotensin ii
growth factor
case control