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Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum.

Mie Korslund Wiinblad CrusellTue Haldor HansenTrine NielsenKristine Højgaard AllinMalte C RühlemannPeter DammHenrik VestergaardChristina RørbyeNiklas Rye JørgensenOle Bjarne ChristiansenFemke-Anouska HeinsenAndre FrankeTorben HansenJeannet LauenborgOluf Pedersen
Published in: Microbiome (2018)
GDM diagnosed in the third trimester of pregnancy is associated with a disrupted gut microbiota composition compared with normoglycaemic pregnant women, and 8 months after pregnancy, differences in the gut microbiota signatures are still detectable. The gut microbiota composition of women with GDM, both during and after pregnancy, resembles the aberrant microbiota composition reported in non-pregnant individuals with type 2 diabetes and associated intermediary metabolic traits.
Keyphrases
  • pregnancy outcomes
  • pregnant women
  • preterm birth
  • genome wide
  • gestational age
  • gene expression