Administering atropine and ketamine before less invasive surfactant administration resulted in low pain scores in a prospective study of premature neonates.
L BourgoinL CaeymaexF DecobertC JungC DananXavier DurrmeyerPublished in: Acta paediatrica (Oslo, Norway : 1992) (2018)
Atropine plus ketamine before LISA resulted in low pain scores and stable haemodynamic parameters, but prolonged desaturations or apnoea leading to tracheal intubation were frequently observed.