Acute metabolic and cardiovascular effects of mirabegron in healthy individuals.

Rebecca K C LohMelissa F FormosaAndre La GercheAnne T ReutensBronwyn A KingwellAndrew L Carey

Published in: Diabetes, obesity & metabolism (2018)

A 100-mg dose of mirabegron increases energy expenditure and supraclavicular skin temperature in a β3-adrenoceptor-specific manner, without the off-target elevations in blood pressure or heart rate observed at higher doses.

Keyphrases

heart rate
blood pressure
heart rate variability
liver failure
respiratory failure
hypertensive patients
soft tissue
aortic dissection
drug induced
hepatitis b virus
type diabetes
blood glucose
mechanical ventilation